Safety and Efficacy of Low-Dose Medical Cannabis Oils in Multiple Sclerosis (MS)

The use of cannabis as medical therapy to treat chronic pain and spasticity in patients with multiple sclerosis (MS) is increasing. However, the evidence on safety when initiating treatment with medical cannabis oils is limited. The aim of this article is to explore the safety of sublingual medical cannabis oils in patients with MS based …

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Cannabinoids, Medical Cannabis, and Colorectal Cancer Immunotherapy

Colorectal cancer is a major public health problem. Unfortunately, currently, no effective curative option exists for this type of malignancy. The most promising cancer treatment nowadays is immunotherapy which is also called biological or targeted therapy. This type of therapy boosts the patient’s immune system ability to fight the malignant tumor. However, cancer cells may …

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Medical Cannabis for the Treatment of Fibromyalgia

Fibromyalgia is one of the most common chronic pain syndromes. It is characterized by diffuse musculoskeletal pain, in addition to extreme fatigue and mood and sleep disturbances. The pathogenesis of fibromyalgia is not clear. It usually affects women more than men and has a genetic preponderance. Its prevalence in the general population is estimated to be approximately …

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Medical Cannabis Treatment in Autism: A Systematic Review

There has been a dramatic increase in the number of children diagnosed with autism spectrum disorders (ASD) worldwide, and with that, anecdotal evidence of possible therapeutic effects of cannabis products has emerged as well. The aim of this article is to characterize the epidemiology of ASD patients receiving medical cannabis treatment and to describe its …

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Medical Cannabis for Neuropathic Pain

Many cultures throughout history have used cannabis to treat a variety of painful ailments. Neuropathic pain is a complicated condition that is challenging to treat with our current medications. Recent scientific discovery has elucidated the intricate role of the endocannabinoid system in the pathophysiology of neuropathic pain. As societal perceptions change, and legislation on medical …

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Medical Cannabis for Psychiatric, Movement and Neurodegenerative Disorders

The discovery of endocannabinoid’s role within the central nervous system and its potential therapeutic benefits have brought forth rising interest in the use of cannabis for medical purposes. The present review aimed to synthesize and evaluate the available evidence on the efficacy of cannabis and its derivatives for psychiatric, neurodegenerative and movement disorders. A systematic …

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A Brief Background on Cannabis: From Plant to Medical Indications

Cannabis has been used as a medicinal plant for thousands of years. As a result of centuries of breeding and selection, there are now over 700 varieties of cannabis that contain hundreds of compounds, including cannabinoids and terpenes. Cannabinoids are fatty compounds that are the main biological active constituents of cannabis. Terpenes are volatile compounds …

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Indica v. Sativa v. Hybrid: Understanding the Basics

When cannabis consumers think of “indica” they generally think that indica strains are physically sedating and perfect for relaxing with a movie or as a nightcap before bed. However, with “sativa” strains, people typically conceptualize them as ‘energizing’ and having uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects. Hybrid …

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